Pharmacological evaluation of Tabernaemontana divaricata Linn. (R.Br.) - Phytochemical Screening, Pharmacological Evaluation & Herbal formulation

by Jain, Sachin
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Jain, Sachin Pharmacological evaluation of Tabernaemontana divaricata Linn. (R.Br.) - Phytochemical Screening, Pharmacological Evaluation & Herbal formulation
Jain, Sachin - Pharmacological evaluation of Tabernaemontana divaricata Linn. (R.Br.) - Phytochemical Screening, Pharmacological Evaluation & Herbal formulation

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Description

Abstract: The aim of the present study was to assess the anti-fertility activity of ethanolic extracts of Tabernaemontana divaricata (TD) leaves in estrogenic activity models in immature female rats. Mature green leaves of TD were collected and authenticated. Extractions of the dried leaves were carried out with ethanol in a Soxhlet s apparatus. For estrogenic activity, the extracts were administered orally once daily at a dose of 200 and 400 mgkg1, and the activity was compared with the standard drug ethinyl estradiol(0.02 mg). The extracts caused ignificant increase in uterine weight compared to the control. The ethanolic extract exhibited estrogenic activity. The histological study of epithelium tissues with the 400mg of TD extract-treated animals showed increases in the height of the luminal epithelium and loose edematous stroma when compared with the 200 mg of TD extract-treated group of animals. However, this was better than the control group of animals. Enhanced uterine weight and increase in the height of luminal epithelium and histological characteristics suggest that TD extract may be useful in anti-fertility therapy.

Contributors

Author:
Jain, Sachin

Further information

Biography Artist:
Mr. Sachin K. Jain M. Pharm. has completed his graduation and post graduation from BR Nahata College of Pharmacy, Mandsaur MP.He has worked as a Assistant Professor in College of Pharmacy, IPS Academy, Indore.Mr. Jain's major fields of interest are Herbal Drug Research, Standardization of Crude Drugs and various Pharmacological activities.
Language:
Englisch
Number of Pages:
80
Media Type:
Taschenbuch
Publisher:
LAP Lambert Academic Publishing

Master Data

Product Type:
Paperback book
Release date:
16 July 2012
Package Dimensions:
0.229 x 0.152 x 0.005 m; 0.168 kg
GTIN:
09783659182730
DUIN:
45V8MH520GR
£38.99
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