Exploring the potential of high viscosity HPMC for SR matrix tablets
by Dua, Kamal
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Sustained release (SR) profiles from tablets can be achieved using various approaches and monolithic matrix system is one of them. However, drug solubility is one of the various considerations in the development of SR matrix tablets. The difficulty in retarding the drug release from SR matrix tablets is intensified with the use of extremely water soluble drugs. Therefore, the manuscript explain the development of SR matrix tablets containing an extremely water soluble model drug using high viscosity HPMC as the release retarding polymer. This approach may provide researchers with novel ideas in the development of SR release matrix tablets.
Choon Wei, Thian
Dr. Kamal has more than 9 years of experience in academia and research. Dr Dua is a seasoned researcher, and has more than 50 research articles to his credit in numerous indexed journals. He has also given more than 45 presentations in various conferences. He has special interest in solubility characteristics of poorly water soluble drugs.
Number of Pages:
LAP Lambert Academic Publishing
19 June 2013
0.22 x 0.15 x 0.004 m; 0.136 kg